请使用支持JavaScript的浏览器!
主营:抗体、抗鸡、免疫沉淀、神经细胞标记、二抗、阻断试剂
℡ 4000-520-616
℡ 4000-520-616
Aves Labs/anti-TREM2 (TREM2)/20µg (TREM2-0020)
产品编号:20µg(TREM2-0020)
市  场 价:¥2380.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$119.00
品      牌: Aves Labs
公      司:Aves Labs, Inc.
公司分类:
Aves Labs/anti-TREM2 (TREM2)/20µg (TREM2-0020)
商品介绍

Our anti-TREM2 chicken primary antibody from AvesLabs is manufactured in-house. It detectsTREM2, and is purified. It is provided in liquid form.

Volume: 100µL (TREM2-0020) or 500µL (TREM2-0100)

Concentration: 0.2mg/mL

Clonality: Polyclonal

Form: Purified

Host Species: Chicken

Antibody Isotype: IgY

Species Reactivity: Human, Mouse, Rat

Applications: ICC, WB

Immunogen: Purified recombinant extracellular domain of human TREM2 (Uniprot Q9NZC2) expressed in E.Coli

Protein Name / Synonyms: Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2

Target Description: Triggering receptor expressed on myeloid cells 2, TREM2, is a type I transmembrane innate immune receptor predominantly expressed by microglia in the central nervous system and is genetically linked to the risk for Alzheimer’s disease (Schmid, C.D., et al., 2002). TREM2 has been shown to be a specific marker for alternatively activated microglia known as M2 cells (Cherry, J.D. et al., 2014). TREM2 binds to its adaptor, DNAX-activating protein (DAP12) on the surface of microglia to enact innate immune responses and downstream cellular responses or signaling pathways (Jay,T.R, et al., 2017). TREM2 has important roles in microglial phagocytosis of apoptotic neurons, damaged myelin, and amyloid plaques (Gratuze, M., et al., 2018). In early brain development, TREM2 is essential for synaptic pruning (Filipello, F. et al., 2018).

Gene ID: TREM2

Physical State: Liquid

Conjugate: Unconjugated

Production Notes: Eggs from hens hyperimmunized with target were used to prepare an IgY fraction which was then subjected to antigen-specific affinity purification

Validation and Application Notes

Molecular Weight: 36 kDa

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Storage

Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. Do not freeze these antibodies unless you want to store them for longer periods of time. Note, however, that each time an antibody preparation is frozen, about half of its binding activity is lost.

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.

↑ back to top

品牌介绍
Aves Labs是一家成立于上世纪九十年代,专注于高亲和性鸡源抗体的研发和准备,生物医药和生命科学行业全球*的鸡多克隆抗体(IgY)及定制抗体/多肽/免疫试剂的专业公司。Aves Labs在鸡源神经系统标志蛋白/抗体研究领域拥有独特优势,不仅品种多样,质量优良,而且适用于人/大小鼠等多个物种的神经系统研究,包括神经元/胶质细胞/雪旺细胞的各亚细胞结构免疫双标/免疫共沉淀研究。公司独有的技术及优质抗体产品有助于全球科研人员更为便捷的解决学术研究及应用研发课题。除了丰富的产品线外,Aves Labs还为客户提供优质的抗体定制服务,您只需要提供需要研究的重组蛋白或合成多肽,我们即可为您生产优质的鸡源多克隆抗体。
自营商城图标
厂家直采
全球直采 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔